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Repeated administration of subanesthetic intravenous ketamine may prolong the rapid decrease in suicidal ideation (SI) elicited by single infusions. The purpose of this secondary analysis was to evaluate reduction in SI with a single ketamine infusion compared with an active control, and prolonged suppression of SI with repeated and maintenance infusions. In TRD, single and...

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Obsessive-compulsive disorder (OCD) is a highly prevalent and disabling neuro-psychiatric condition for which currently available treatments are insufficiently effective and alternatives merit priority attention. Psilocybin may represent a safe and effective avenue for treatment of individuals affected by this condition. In this chapter we briefly introduce OCD symptoms, epidemiology, as well as relevant hypotheses on...

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  It has been discovered over the years that psychedelics have been the source of inspiration for creativity for musicians, artists, scientists as they make use of psychedelics to heighten and increase their rate of creativity. For this reason, many people have taken the cue to turn to magic mushrooms to improve their cognitive functions....

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While anecdotal evidence suggests that select 5-hydroxytryptamine 2A receptor ligands, including psilocybin, may have long-lasting therapeutic effects after limited dosing in headache disorders, controlled investigations are lacking.   This exploratory article suggests there is an enduring therapeutic effect in migraine headache after a single administration of psilocybin. The separation of acute psychotropic effects and lasting...

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  Alcohol use disorder represents a serious clinical, social and personal burden on its sufferers and a significant financial strain on society. Current treatments, both psychological and pharmacological are poor, with high rates of relapse after medical detoxification and dedicated treatment programs. The earliest historical roots of psychedelic drug-assisted psychotherapy in the 1950s were associated...

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  This article examines the role of trauma in psychiatric morbidity and analogous psycho-neurobiological changes. Trauma is a necessary criterion for Post-Traumatic Stress Disorder (PTSD), however, trauma history is highly correlated with a variety of psychiatric conditions. Some evidence suggests that Major Depressive Disorder (MDD) is the most common psychiatric condition that arises following trauma....

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  Social anxiety disorder (SAD) is a prevalent and often debilitating psychiatric disorder that can assume a chronic course even when treated. Despite the identification of evidence-based pharmacological and behavioral treatments for SAD, much room for improved outcomes exists and 3,4-methylenedioxymethamphetamine (MDMA) has been proposed as a promising adjunctive treatment to psychological interventions for disorders...

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  Despite decades of medical research for what remains a substantial public health problem, there are no medications approved by the U.S. Food and Drug Administration for the treatment of cocaine use disorder. Standard behavioral treatments, meanwhile, are beset by high failure rates. A line of pharmacotherapy research that holds promise is modulation of glutamate...

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As you prepare to enjoy your magic mushroom trip, we recommend for you to watch exciting and interesting movies to enhance your experience during your mushroom trips. The movies on the following list are amazing movies that are certainly going to make your psychedelic trips memorable as they are fun to watch, filled with bright...

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