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    From the beginning of therapeutic research with psychedelics, music listening has been consistently used as a method to guide or support therapeutic experiences during the acute effects of psychedelic drugs. Recent findings point to the potential of music to support meaning-making, emotionality, and mental imagery after the administration of psychedelics, and suggest that...

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    Psilocybin-occasioned mystical experiences have been linked to persisting effects in healthy volunteers including positive changes in behavior, attitudes, and values, and increases in the personality domain of openness. In an open-label pilot-study of psilocybin-facilitated smoking addiction treatment, 15 smokers received 2 or 3 doses of psilocybin in the context of cognitive behavioral therapy...

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     Recent evidence indicates that psilocybin with psychological support may be effective for treating depression. Some studies have found that patients with depression show heightened amygdala responses to fearful faces and there is reliable evidence that treatment with SSRIs weakens amygdala responses. We hypothesised that amygdala responses to emotional faces would be altered post-treatment...

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  Psilocybin with psychological support is showing promise as a treatment model in psychiatry but its therapeutic mechanisms are poorly understood despite a growing body of research. Today, our article aims to provide readers with an understanding pertaining to the post-treatment brain changes relative to previously observed acute effects of psilocybin and other ‘psychedelics’ related...

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  Microdosing psychedelics is the repeated use of small doses of, for example, lysergic acid diethylamide (LSD) and psilocybin, typically for a few weeks. Despite the popular and scientific attention in recent years and claims by users that it has therapeutic value in affective disorders like depression, little scientific knowledge is available to back this....

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MDMA & PTSD: A Comprehensive Review   For several mental health disorders, including posttraumatic stress disorders (PTSD), there are not many available treatment options. Recently, there has been renewed interest in the potential of methylenedioxymethamphetamine (MDMA) to restore function for patients with these disorders. The primary hypothesis is that MDMA, via prosocial effects, increases the...

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  Several lines of evidence suggest that classic (5HT2A agonist) hallucinogens have clinically relevant effects in alcohol and drug addiction. Although recent studies have investigated the effects of psilocybin in various populations, there have been no studies on the efficacy of psilocybin for alcohol dependence.   However, the findings from this study provide a strong...

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  Psilocybin and other 5-hydroxytryptamine2A agonist classic psychedelics have been used for centuries as sacraments within indigenous cultures. In the mid-twentieth century they were a focus within psychiatry as both probes of brain function and experimental therapeutics. By the late 1960s and early 1970s these scientific inquires fell out of favor because classic psychedelics were being...

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    There is a substantive clinical literature on classical hallucinogens, most commonly lysergic acid diethylamide (LSD) for the treatment of alcohol use disorder. Chemically related to serotonin, LSD was initially hypothesized to produce a psychosis like state. Later, LSD was reported to have benefits in the treatment of addictions. However, widespread indiscriminate use and reports...

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The Flavor Profile and Characteristics of the Most Popular Psilocybin Varieties   With more than 180 species of psilocybin mushrooms, including the famous psilocybin cubensis, grow wildly around the globe. With that said, today, we’ll take a look at the unique profiles and characteristics of psilocybin varieties.   #1:  Psilocybe Semilanceata (“Liberty Caps”)   Synopsis:...

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